David earned his B.A. in Biology and Chemistry at Hanover College in Hanover, Indiana. In 2014, he matriculated into the MD/PhD program at the University of Kentucky. During his first two years of medical school, David worked with Dr. Moises Huaman of the Division of Infectious Disease to study the relationship between tuberculosis and cardiovascular disease. For his graduate work, David joined Dr. Venditto's lab in the College of Pharmacy to study the role of antibodies in cardiovascular disease. In his graduate work, David has identified a novel cardiovascular biomarker consisting of ApoA-I and IgG and published a paper describing this finding in the Atherosclerosis, Thrombosis, and Vascular Biology. He anticipates completing his graduate work in the department in the next year. David's long term career interest is to work as an infectious disease physician with a research program focused on immunomodulation in transplant patients.
The interplay between the immune system and the development of cardiovascular disease has been well established and our understanding of this connection continues to grow. My curiosity of how the immune system alters disease positions me at the nexus of these fields with significant translational impact. My current project has the potential to improve patient care through the discovery of novel immune biomarkers capable of predicting disease outcomes. Through this research, I will develop tools to identify patients at high risk for cardiovascular disease progression and explore novel strategies to modulate the immune system to improve clinical outcomes.
American Heart Association Predoctoral Fellowship 2019-2020.
Pharmaceutical Sciences Excellence in Graduate Achievement Fellowship -2018 to 2019
TL-1 Grant from University of Kentucky Center for Clinical and Translational Science TL1TR001997 -2016 to 2018
Henson, D., Samman-Tahhan, A., Nardo, D. Quyyumi, A., Venditto, V. Association Between ApoA-I (Apolipoprotein A-I) Immune Complexes and Adverse Cardiovascular Events. Atherosclerosis, Thrombosis and Vascular Biology. 39(9), 1884-1892. 2019.
Henson, D., Chou, C., Sakurai, N., Egawa, T. A Silencer-Proximal Intronic Region Is Required for Sustained CD4 Expression in Postselection Thymocytes. Journal of Immunology. 192(10), 4620-7. 2014.
Huaman, M., Henson, D., Ticona, E., Sterling, T., Garvy, B. Tuberculosis and Cardiovascular Disease: Linking the Epidemics. Tropical Diseases, Travel Medicine and Vaccines. 1(1), 10. 2014.
Huaman, M., Kryscio, R., Fichtenbaum, C., Henson, D., Salt, E., Sterling, T., Garvy, B. Tuberculosis and risk of Myocardial Infarction: a Propensity Score-Matched Analysis. Epidemiology and Infection. 145(7), 1363-1367. 2017.
Huaman, M., Ticona, E., Miranda, G., Kryscio, R., Mugruza, R., Aranda, E., Rondan, PL., Henson, D., Ticona, C., Sterling, TR., Fichtenbaum, CJ., Garvy, B. The Relationship Between Latent Tuberculosis and Acute Myocardial Infarction. Clinical Infections Disease. 66(6), 886-892. 2018.
Huaman, M., Henson, D., Rondan, P., Ticona, E., Miranda, G., Kryscio, R., Mugruza, R., Aranda, E., Ticona, C., Abarca, S., Heredia, P., Aguirre, A., Sterling, T., Garvy, B., Fichtenbaum, C. Latent Tuberculosis Infection is Associated with Increased Unstimulated Levels of Interferon-gamma in Lima, Peru. Public Library of Science One. 13(9), e0202191. 2018.