Name Graduate Department Dissertation Title PhD Mentor Residency Ryan Cloyd, MD, PhD Physiology "The Role of Microtubule-Associated Protein Tau in Neuronal Excitability and Epileptogenesis" Bret Smith, PhD Neurological Surgery - Indiana University SOM, Indianapolis, IN Charles Coomer, MD, DPhil Virology (Oxford - NIH) "Identifying Biophysical Determinants of Virus-Cell Fusion through Live-Cell Imaging" Alex Compton, PhD and Sergi Padilla-Parra, PhD Pediatrics - Boston Children's Hospital, Boston, MA David Henson, MD, PhD Pharmaceutical Sciences "Identification and Characterization of Epitope Specific Immune Responses in Humans and Mice" Vincent Venditto, PhD Internal Medicine - U Kentucky Med Ctr, Lexington, KY

Name Graduate Department Dissertation Title PhD Mentor Residency Jeremy A. Johnson, MD, PhD Toxicology & Cancer Biology "Examining the Role of Metabolic Pathways as Therapeutic Modalities for Triple Negative Breast Cancer" Mark Evers, MD, FACS Pathology - Johns Hopkins Hosp, Baltimore, MD Meghan Haney, MD, PhD Molecular & Cellular Biochemistry "Therapeutic Targeting of Leukemia Stem Cells to Prevent T-Cell Acute Lymphblastic Leukemia Relapse" Jessica Blackburn, PhD Pediatrics - Cincinnati Children's Hosp Med Ctr, Cincinnati, OH Jeff Chen, MD, PhD Physiology "Involvement of the Renin Angiotensin System in Marfan Syndrome Associated Thoracic Aortic Aneurysms" Alan Daugherty, PhD Internal Medicine PSTP - U Texas Southwestern Med Sch, Dallas, TX Brandon Farmer, MD, PhD Physiology "APOE as a Metabolic Regulator in Humans, Mice, and Astrocytes" Lance Johnson, PhD Anesthesiology - Vanderbilt Univ Med Ctr, Nashville, TN

Name Graduate Department Dissertation Title PhD Mentor Residency Luke Heil, MD, PhD Microbiology, Immunology, and Molecular Genetics "The Role of CD8 T Cell Immunodominance and Regulatory T Cells in Neonatal Immunity to Influenza Virus" Beth A. Garvy, PhD Pediatrics - U Kentucky Med Ctr, Lexington, KY Andrew Welleford, MD, PhD Anatomy & Neurobiology "Autologous Peripheral Nerve Grafts to the Brain for the Treatment of Parkinson's Disease" Greg Gerhardt, PhD Neurology - U Kentucky Med Ctr, Lexington, KY Jacqueline Kulbe, MD, PhD Neuroscience "Neuroprotective Strategies Following Experimental Traumatic Brain Injury: Lipid Peroxidation-Derived Aldehyde Scavenging and Inhibition of Mitochondrial Permeability Transition" Edward D. Hall, MD Psychistry/Research - UC San Diego Med Ctr, San Diego, CA Scott Thalman, MD, PhD Biomedical Engineering "Calibrated Short TR Recovery MRI for Rapid Measurement of Brain-Blood Partition Coefficient and Correction of Quantitative Cerebral Blood Flow" Ai-Ling Lin, PhD Med-Prelim/Radiology - U Kansas SOM, Kansas City, MO | Diagnostic Radiology - U Kansas SOM, Kansas City, MO Joshua Mitchell, MD, PhD Molecular and Cellular Biochemistry "Computational Tools for the Untargeted Assignment of FT-MS Metabolomics Datasets" Hunter N. B. Moseley, PhD Los Alamos National Laboratory

Name Graduate Department Dissertation Title PhD Mentor Residency Evan Lynch, MD, PhD Microbiology, Immunology, and Molecular Genetics "Elucidating the Complex Signaling Events Driving Intestinal Stem Cell Plasticity Following Injury" Terrence A. Barrett, MD Plastic Surgery (Integrated) - U Kentucky Med Ctr, Lexington, KY

Name Graduate Department Dissertation Title PhD Mentor Residency Kristin B. Linscott, MD, PhD Molecular and Cellular Biochemistry "Discovering a Novel Antifungal Target in Downstream Sterol Biosynthesis Using a Squalene Synthase Functional Motif" Joseph Chappell, PhD Pediatrics/Medical Genetics and Genomics - University of Alabama Med Ctr, Birmingham, AL Gregory J. Wehner, MD, PhD Biomedical Engineering "Validation, Optimiztion, and Image Processing of Spiral Cine Dense Magnetic Resonance Imaging for the Quantification of Left and Right Ventricular Mechanics" Brandon Fornwalt, MD, PhD Diagnostic Radiology/Research - Barnes-Jewish Hospital, St. Louis, MO Christopher Brown, MD, PhD Anatomy & Neurobiology "The Default Mode Network and Executive Function: Influence of Age, White Matter Connectivity, and Alzheimer's Pathology" Brian T. Gold, PhD Neurology - Hospital of the University of Pennsylvania, Philadelphia, PA Eseosa Ighodaro, MD, PhD Anatomy & Neurobiology "Studying Vascular Morphologies in the Aged Human Brain Using Large Autopsy Datasets" Peter Nelson, MD, PhD Neurology - Mayo Clinic School of Grad Med Educ, Rochester, MN

Name Graduate Department Dissertation Title PhD Mentor Residency Erin Wolf Horrell, MD, PhD Physiology "Regulation of UV-Protective Pathways Downstream of the Melanocortin 1 Receptor in Melanocytes" John D'Orazio, MD, PhD General Surgery - Vanderbilt Univ Med Ctr, Nashville, TN Edita M. Klimyte, MD, PhD Molecular and Cellular Biochemistry "Elucidating Binding, Fusion, and Entry of Human Metapneumovirus" Rebecca E. Dutch, PhD Dermatology - University of Arkansas for Medical Sciences, Little Rock, AR

Name Graduate Department Dissertation Title PhD Mentor Residency Lucas S. Broster, MD, PhD Behavioral Science "Emotional Enhancement and Repetition Effects During Working Memory in Persons with Mild Cognitive Impairment" Yang Jiang, PhD Psychiatry - University of California, San Francisco, CA

Name Graduate Department Dissertation Title PhD Mentor Residency Dustin B. Stephens, MD, PhD Behavioral Science “Primary and secondary prevention of hepatitis C virus among rural Appalachian people who use drugs” Jennifer R. Havens, PhD, MPH Psychiatry - Harbor-UCLA Medical Center, Los Angeles, CA Dustin P. Brown, MD, PhD Anatomy & Neurobiology "Target-Directed Biosynthetic Evolution: Redirecting Plant Evolution to Genomically Optimize a Plant's Pharmacological Profile" Greg A. Gerhardt, PhD Radiology - UC San Diego, CA

Name Graduate Department Dissertation Title PhD Mentor Residency Andres Chang, MD, PhD Molecular and Cellular Biochemistry "Early Events of Human Metapneumovirus Infection" Rebecca E. Dutch, PhD Internal Medicine - Emory University, Atlanta, GA Mellani Lefta, MD, PhD Physiology     Pediatrics - Children's Hospital of the King's Daughters - Norfolk, VA Abdelghaffar Salous, MD, PhD Pharmacology "Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice"   General Surgery - Sinai Hospital of Baltimore, Baltimore, MD

Name Graduate Department Dissertation Title PhD Mentor Residency Zachary Fulkerson, MD, PhD Physiology "Lysophosphatidic Acid Production and Signaling in Platelets" Susan S. Smyth, MD, PhD Internal Medicine - Indiana University, Indianapolis, IN Carmen Kiper, MD, PhD Physiology "Strain-specific Cardiomyocyte Composition Regulates Cardiac Growth Potential" Jonathan Satin , PhD Pediatrics - University of Louisville, Kosair Children's Hospital, Louisville, KY Caitlin Latimer, MD, PhD Pharmacology   Nada Porter, PhD Anatomic Pathology - University of Washington Affiliated Hospital - Seattle, WA Scott Silva, MD, PhD Biochemistry "A Novel Role for VEGF Signialling in Carcinoid Tumors" B. Mark Evers, MD, FACS General Surgery Internship - Vanderbilt University Medical Center, Nashville, TN | Radiation Oncology Residency - Loyola University Medical Center, Chicago, IL Christopher Simmons, MD, PhD Physiology   Steven Estus, PhD Pediatrics - University of Kentucky, Lexington, KY

Name Graduate Department Dissertation Title PhD Mentor Residency Natalie Wallis, MD, PhD Pharmacology   Michael W. Kilgore, PhD Pediatrics - University of Kentucky, Lexington, KY

Name Graduate Department Dissertation Title PhD Mentor Residency Romulo Albuquerque, MD, PhD Physiology/Ophthalmology "Soluble vascular endothelial growth factor receptor 2: an endogenous inhibitor of lymphangiogenesis" Jayakrishna Ambati, MD Ophthalmology - University of Kentucky, Lexington, KY James Butler, MD, PhD Microbiology & Immunology "Mechanisms governing the zonal activity of alpha-fetoprotein enhancer EIII" Brett Spear, PhD Psychiatry - UT Southwestern, Dallas, TX Willie Craft Jr., MD, PhD Molecular and Cellular Biochemistry "Investigation of the proteolytic processing of the hendra virus fusion protein" Rebecca E. Dutch, PhD Internal Medicine - Hahnemann University, Philadelphia, PA Michelle Stephens Humeidan, MD, PhD Anatomy & Neurobiology "Glutamate regulation in the hippocampal trisynaptic pathway in aging and status epilepticus" Greg Gerhardt, PhD Anesthesiology - Ohio State University, Columbus, OH Nirmal Ravi, MD, PhD Biomedical Engineering "Regeneration of damaged growth plate using IGF-I plasmid releasing porous PLGA scaffolds" David A. Puleo, PhD Family Medicine - Providence Hospital, Georgetown, Washington D.C.

Name Graduate Department Dissertation Title PhD Mentor Residency Karrie Grear, MD, PhD Physiology "Uncoupling protein-2 splicing efficiency and human disease" Steven Estus, PhD Neurology - Wake Forest University, Winston-Salem, NC Jeff Yates, MD, PhD Physiology "The genetic regulation of the response of hematopoietic stem/ progenitor cells to the cytostatic agent hydroxyurea" Gary Van Zant, PhD Internal Medicine & Pediatrics - Indiana University, Indianapolis, IN

Name Graduate Department Dissertation Title PhD Mentor Residency Janelle Reed, MD, PhD Anatomy & Neurobiology "Alterations in proteasome subunit expression and influences on the inflammatory response" Annadora J. Bruce-Keller, PhD Emergency Medicine - University of Kentucky, Lexington, KY

Name Graduate Department Dissertation Title PhD Mentor Residency Mark A. Wurth, MD, PhD Biochemistry "Role of actin dynamics in paramyxovirus F mediated membrane fusion events" Rebecca E. Dutch, PhD Internal Medicine & Pediatrics - University of Kentucky, Lexington, KY Kristine S. Ziemba, MD, PhD Physiology "Targeting axon growth from neurons transplanted into the central nervous system" George M. Smith, PhD Neurology - Mayo Clinic, Pheonix, AZ

Name Graduate Department Dissertation Title PhD Mentor Residency Brian K. Day, MD, PhD Anatomy & Neurobiology "Microelectrode array studies of normal and disease-altered L-glutamate regulation in the mammalian central nervous system" Greg Gerhardt, PhD Neurology - Washington University, St. Louis, MO

Name Graduate Department Dissertation Title PhD Mentor Residency Michael W. Manning, MD, PhD Physiology "Differential effects of doxycycline, a broad spectrum inhibitor of matrix metalloproteinases" Alan Daugherty, PhD, DSc, FAHA Surgery Internship - University of Kentucky, Lexington, KY | Anesthesiology - University of Kentucky, Lexington, KY Erin L. Manning, MD, PhD Physiology "Regulation of telomere length in murine hematopoietic cells" Gary Van Zant, PhD Anesthesiology - University of Kentucky, Lexington, KY Xuan Nguyen, MD, PhD Anatomy & Neurobiology "Aging and the dynorphinergic system: evaluation of memory and motor systems in prodynorphin knockout mice" Guoying Bing, PhD Internal Medicine Internship - University of Cincinnati, Cincinnati, OH | Diagnostic Radiology Residency - University of Kentucky, Lexington, KY

Name Graduate Department Dissertation Title PhD Mentor Residency Christina S. Hines, MD, PhD Molecular and Cellular Biochemistry "X-ray crystallographic and functional studies on the neuropeptidase neurolysin" David W. Rodgers, PhD Psychiatry - Johns Hopkins University, Baltimore, MD

Name Graduate Department Dissertation Title PhD Mentor Residency Joshua L. Hood, MD, PhD Microbiology & Immunology "The association of calpain and its regulatory proteins with the endoplasmic reticulum and golgi apparatus" Thomas L. Roszman, PhD Clinical Pathology - Washington University, St. Louis, MO Shane W. Rau, MD, PhD Physiology "Mechanisms of estradiol-mediated protection against stroke-like injury" Phyllis M. Wise, PhD Psychiatry - University of Virginia Health System, Charlottesville, VA

Name Graduate Department Dissertation Title PhD Mentor Residency Dena Dubal, MD, PhD Physiology "Estradiol Protects the Brain Against Stroke Injury: Potential Mechanisms of Action" Phyllis M. Wise, PhD Neurology - University of California, San Francisco, CA

Name Graduate Department Dissertation Title PhD Mentor Residency Melisa W. Mullins, MD, PhD Microbiology & Immunology   Charles Snow, PhD Pediatrics - William Beaumont Hospital Mathew A. Nicholls, MD, PhD Biochemistry "MR studies of the acute response of the rhesus CNS to the neurotoxin MPTP" Thomas C. Vanaman, PhD Orthopaedic Surgery - University of Kentucky, Lexington, KY

Name Graduate Department Dissertation Title PhD Mentor Residency Gregory E. Cooper, MD, PhD Microbiology & Immunology     Neurology - University of Iowa Hospitals & Clinics, Iowa City, IA

Name Graduate Department Dissertation Title PhD Mentor Residency Gregory N. Barnes, MD, PhD Biochemistry "The role of Ca+2 dependent protein kinases and protein phosphatase 2A in the kindling model of epilepsy"   Pediatrics - Washington University/St. Louis Children's Hospital, St. Louis, MO