Denison University -2013
I am from Rochester, NY and completed my undergraduate degree at Denison University, which is outside of Columbus, OH. I then moved to Gainesville, FL for a year to work at the University of Florida as a clinical research coordinator for gene therapy trials in patients with Pompe Disease. After my year in Florida, I moved to Lexington, KY. I chose the University of Kentucky MD/PhD program because it felt the most like home while I was interviewing. I could easily picture myself spending the next 8 years of my life with the people in the program at Kentucky and have been very happy with my decision!
My current research in Dr. Jessica Blackburn's lab focuses on leukemia stem cell signaling and self-renewal pathways. Leukemia stem cells make up a very small population of leukemia cells and are responsible for leukemia relapse in vivo. We are looking at the signaling pathways in these stem cells trying to find drug targets to block self-renewal of these cells. We are using zebrafish as a model organism as they allow for in vivo study of leukemia stem cells and large volume drug screens. I am also working on a clinical project using cell-free DNA as a marker to measure leukemia relapse in patients.
Visit our lab's website:
NIH Training Grant T32CA165990
UKY CCTS PSMRF - July 2015
2018 AAP/ASCI/APSA Annual Meeting Travel Award Recipient
2018 AAP/ASCI/APSA Annual Meeting
2018 AACR Annual Meeting
- Smith, BK ; Renno, MS ; Green, MM ; Sexton, TM ; Lawson, LA ; Martin, AD ; Corti, M.; Byrne, BJ "Respiratory motor function in individuals with centronuclear myopathies." Muscle & nerve 53, 2 (2016): 214-21. [PubMed Link] | [ Full text ]
- Corti, M.; Elder, M.; Falk, D.; Lawson, L.; Smith, B.; Nayak, S.; Conlon, T.; Clément, N.; Erger, K.; Lavassani, E.; Green, M.; Doerfler, P.; Herzog, R.; Byrne, B. "B-Cell Depletion is Protective Against Anti-AAV Capsid Immune Response: A Human Subject Case Study." Molecular therapy. Methods & clinical development 1, (2014): [PubMed Link] | [ Full text ]